Peer-reviewed veterinary case report
Using clot tests to guide blood transfusions in dogs with bleeding
By Langhorn, Rebecca et al.·Published in Acta veterinaria Scandinavica·2019·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Thromboelastography-guided transfusion in dogs with hypocoagulable disorders: a case series.
- Species:
- dog
Plain-English summary
Four dogs with bleeding issues due to different conditions, including rodent poison ingestion and immune-mediated thrombocytopenia (a condition where the immune system attacks platelets), were treated using a special test called thromboelastography (TEG). This test helped the veterinarians decide how much fresh frozen plasma each dog needed to help their blood clot properly. By using TEG, the vets could customize the treatment for each dog, improving their chances of recovery. All four dogs received tailored transfusion therapy based on their specific needs.
People also search for: dog bleeding problems treatment · rodenticide poisoning in dogs · immune-mediated thrombocytopenia in dogs
Abstract
BACKGROUND: Thromboelastography (TEG) is a global whole blood hemostasis assay which includes plasma as well as cellular components of hemostasis in the analysis and follows the quality and dynamics of clot development, stabilization, and lysis. In human medicine TEG is also a valuable asset in the therapeutic setting, allowing evaluation of the effect of transfusion therapy in vitro. This case series describes the use of TEG as a guiding tool for transfusion therapy in four dogs with hypocoagulable hemostatic disorders. CASE PRESENTATION: Four dogs presented with hypocoagulable disorders of hemostasis, diagnosed as rodenticide intoxication, angiostrongylosis, disseminated intravascular coagulation following severe systemic inflammation, and immune-mediated thrombocytopenia, respectively. TEG was used as a diagnostic tool as well as a guiding tool in the decision of whether or not, and in what dose, fresh frozen plasma would be of benefit in the treatment protocol for each dog. CONCLUSIONS: TEG may be applied in the therapeutic setting as a means to tailor individual patient transfusion therapy in critically ill dogs with hypocoagulable states.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31331398/