Peer-reviewed veterinary case report
Blood clotting changes in dogs with Leishmania infection
By Bruno, Barbara et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2015·Department of Veterinary Science, Italy·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Thromboelastometric evaluation of hemostasis in dogs infected with Leishmania infantum.
- Species:
- dog
Plain-English summary
A group of 84 dogs with leishmaniasis (a disease caused by a parasite) had their blood tested to check how well it clotted before and after treatment. The tests showed that while the dogs with symptoms had some differences in their blood compared to healthy dogs and those who had been treated, all the results were still within normal ranges. This means that even though the dogs with leishmaniasis showed some changes, their overall ability to clot blood was not severely affected. The findings suggest that standard blood tests for clotting were normal, indicating that treatment may help restore health without major clotting issues.
People also search for: dog leishmaniasis treatment · dog blood clotting test results · symptoms of leishmaniasis in dogs
Abstract
OBJECTIVE: Evaluation of hemostasis using thromboelastometry in dogs with leishmaniasis before and after treatment. DESIGN: Longitudinal observational study. SETTING: University veterinary teaching hospital. ANIMALS: Eighty-four adult, client-owned dogs. MEASUREMENTS AND MAIN RESULTS: Whole blood samples for the coagulation profile were collected from symptomatic dogs with leishmaniasis (group S), asymptomatic dogs with leishmaniasis after treatment (group T), and a control group of healthy dogs (group H). Hemostasis was evaluated by means of standard coagulation profile (prothrombin time, activated partial thromboplastin time, and fibrinogen) and by thromboelastometry (ROTEM). Prothrombin time and activated partial thromboplastin time were within the upper reference range in all 3 groups. Comparison of the ROTEM variables between the 3 groups showed statistically significant differences between group S versus groups T and H, but remaining within the reference ranges. Statistically significant differences in hematocrit and fibrinogen concentrations were noted between groups (group S vs. H: hematocrit P = 0.001, fibrinogen P = 0.002; Group S vs. T: hematocrit P = 0.001, fibrinogen P = 0.001). These variations have interfered with some parameters of the ROTEM profile. CONCLUSIONS: This study showed normal standard coagulation profiles in all 3 groups evaluated. The ROTEM results did not fall outside of the maximum values of the reference ranges.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26096881/