Peer-reviewed veterinary case report
Dog with thymoma tumor containing granular cells and lymphoma cells
By Fukuoka, Ayumi et al.·Published in The Journal of veterinary medical science·2004·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Thymoma in a dog with a part of granular cell proliferation and concurrent lymphoma cells.
- Species:
- dog
Plain-English summary
A 12-year-old male Shiba Inu was brought in with anemia and swollen lymph nodes. X-rays and further examinations revealed a mass in the chest area. The mass was made up of different types of abnormal cells, including some that were linked to lymphoma, a type of cancer. Unfortunately, the dog had a complex tumor that involved both thymoma (a tumor of the thymus gland) and lymphoma. The specific treatment details weren't provided, but this case highlights the importance of thorough testing when unusual symptoms arise in older dogs.
People also search for: Shiba Inu swollen lymph nodes · dog anemia treatment · thymoma in dogs · lymphoma in dogs symptoms
Abstract
A 12-year-old male Shiba dog showed anemia and the swelling of systemic lymph nodes. X-ray and post mortal examinations revealed a anterior mediastinal mass. Histologically, the tumor mass consisted of four different elements; cord-like proliferation of cuboidal epithelial cells, tubular or cystic structures lined with ciliated epithelial cells, proliferation of large round-shaped epithelial cells with PAS-slightly positive granular cytoplasm, and diffuse proliferation of neoplastic lymphocytes. Epithelial cells in cord-like or cystic structures were strongly positive for cytokeratin. Granular or foamy cells were negative for all markers examined and had myelin-like bodies in the cytoplasm by electron microscopy. The neoplastic lymphocytes in the tumor mass were considered being derived from concurrent multicentric lymphoma. Based on these findings, the present case was diagnosed as thymoma with a part of granular cell proliferation and concurrent lymphoma cells.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15240949/