Peer-reviewed veterinary case report
Detecting tick-borne encephalitis virus in dog blood using nested
By Hekrlová, Alena et al.·Published in Berliner und Munchener tierarztliche Wochenschrift·2015·View original on PubMed →
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Original publication title: Tick-borne encephalitis in dogs: application of "nested real-time RT-PCR" for intravital virus detection.
- Species:
- dog
Plain-English summary
A group of dogs in the Czech Republic were tested for tick-borne encephalitis (TBE) after showing signs of neurological issues. Out of 159 dogs, 20 tested positive for the virus using a special blood test, and seven of those showed symptoms like weakness or coordination problems. The testing was done from March to November, and some dogs had both positive blood tests and signs of infection. This study suggests that a new testing method could help detect TBE in dogs more effectively.
People also search for: dog neurological symptoms tick-borne encephalitis · TBE virus in dogs · how to test for tick-borne diseases in dogs
Abstract
Tick-borne encephalitis (TBE) virus is a tick-transmitted virus causing disorders of the nervous system in humans, monkeys, dogs and horses (rarely). At present the detection of TBE infection in dogs is performed by confirmation of seroconversion in paired samples of serum in clinical practice. The intention of the study was the assessment of the possible application of nested real-time RT-PCR for detection of TBE virus in canine blood. The study was carried out in 2011-2012 using samples originating in the Czech Republic, South Moravian region (region with endemic occurrence of TBE). The dogs were randomly selected from the patients visiting the clinic during this time period. Of the total amount of 159 canine blood samples, 20 samples were tested with a PCR-positive result (12.6%). Out of these 20 animals, the neurological clinical symptoms typical of TBE were detected in seven dogs. PCR-positive results were found between March and November. Three dogs were tested with a competitive ELISA-positive result and a "nested real-time RT-PCR"-positive result concurrently. In the group of 159 dogs the value of seroprevalence was found to be 11.3%.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26591386/