Peer-reviewed veterinary case report
Tracking serum amyloid A levels in a cat with pancreatitis over time
By Tamamoto, Takashi et al.·Published in Veterinary clinical pathology·2009·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Time-course monitoring of serum amyloid A in a cat with pancreatitis.
- Species:
- cat
Plain-English summary
A cat with pancreatitis showed high levels of serum amyloid A (SAA), a protein that indicates inflammation, at the start of its illness. After five days of treatment, the SAA levels decreased, and the cat's condition improved. Interestingly, other tests like white blood cell count and a specific enzyme test did not show changes until later in the treatment. Long-term monitoring revealed that SAA levels could help track the cat's recovery and any flare-ups of the disease. The cat responded well to treatment and showed signs of improvement.
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Abstract
Time-course changes in the concentration of serum amyloid A (SAA), a major acute phase protein, were measured in a cat with pancreatitis over an 831-day period and compared with changes in WBC count and feline trypsin-like immunoreactivity (fTLI). SAA concentration was increased at the onset of the disease and gradually decreased over 5 days of treatment with an improvement in the clinical condition. In contrast, fTLI concentration and WBC count were not increased at the onset of the disease but increased gradually during the 5 days of treatment. Long-term monitoring from days 68 to 831 revealed a good correlation between SAA concentration and the reoccurrence of clinical signs in the cat; however, WBC count did not increase even with the exacerbation of disease. These findings suggest that the SAA concentration may be a useful marker for evaluating response to treatment and disease exacerbation in feline pancreatitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19228363/