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Peer-reviewed veterinary case report

Topical fusidic acid and steroid gel works as well as systemic drugs

By Cobb, M A et al.·Published in Veterinary journal (London, England : 1997)·2005·LEO Animal Health, United Kingdom·View original on PubMed

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Original publication title: Topical fusidic acid/betamethasone-containing gel compared to systemic therapy in the treatment of canine acute moist dermatitis.

Species:
dog

Plain-English summary

A group of 104 dogs with acute moist dermatitis, which causes red, itchy, and inflamed skin, were treated with either a topical gel containing fusidic acid and betamethasone or a combination of injectable dexamethasone and oral antibiotics. After seven days, both treatments showed significant improvement in the dogs' skin conditions, with no notable difference in effectiveness between the two options. This means that pet owners can choose either the topical gel or the systemic therapy, as both were effective in treating the skin problem.

People also search for: dog skin infection treatment · dog dermatitis topical gel · best treatment for dog itchy skin

Abstract

The efficacy of a topical preparation containing 0.5% fusidic acid and 0.1% betamethasone-17-valerate was compared to a systemic therapy (comprising a combination of parenteral dexamethasone and oral clavulanate-potentiated amoxycillin) in the treatment of 104 dogs with acute moist dermatitis. Significant improvement was evident after seven days in both treatment groups in all clinical parameters assessed and there was no significant difference in the overall response between the two treatment groups. Staphylococcus intermedius was the most frequently isolated organism from swabs at the first visit (Day 0). No resistance to fusidic acid or clavulanate-potentiated amoxycillin was encountered. The study demonstrates no difference in the clinical improvement achieved in canine acute moist dermatitis following topical or systemic therapy and that both treatment regimes represent effective treatment options for the condition.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15727921/