Peer-reviewed veterinary case report
Cat with severe mouth inflammation improves after special light
By Chien Ju Hou et al.·Published in Photodiagnosis and Photodynamic Therapy·2024·Sheng-Li Cat Hospital, Tainan, Taiwan, NL·View original on DOAJ →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Topical indocyanine green antimicrobial photodynamic therapy for refractory feline chronic gingivostomatitis: A case report
- Species:
- cat
Plain-English summary
A 5-year-old female cat with severe chronic gingivostomatitis (FCGS), which caused painful inflammation in her mouth, was not improving with antibiotics, anti-inflammatory medications, or dental extractions. After trying a new light-based treatment using a special dye (indocyanine green) that targets bacteria, the cat showed quick improvement without any side effects over 13 sessions. Remarkably, she gained weight and, after three years, there were no signs of her mouth condition returning. This case suggests that this new treatment could be a helpful option for cats suffering from FCGS.
People also search for: cat gingivostomatitis treatment · feline chronic gingivostomatitis symptoms · indocyanine green therapy for cats
Abstract
Feline chronic gingivostomatitis (FCGS) is a painful and severe inflammatory mucosal disease in cats that presents significant challenges in treatment. This case study describes a novel approach for a cat with FCGS that was unresponsive to antibiotics, non-steroidal anti-inflammatory drugs, and dental extraction. The cat exhibited rapid improvement after undergoing oral indocyanine green (ICG)-mediated antimicrobial photodynamic therapy (aPDT); however, treatment was discontinued due to an episode of anaphylaxis. Subsequent oral aminolevulinic acid (ALA)-mediated aPDT proved ineffective over nine sessions. The cat was then treated with a topical approach using ICG-aPDT. ICG was prepared by dissolving 5 mg of powder in 3 mL of sterile water, which was applied to the oral gingiva, followed by irradiation with an 810 nm diode laser, delivering a total fluence of 16.8 J/cm2 per session through the skin in two divided doses. The cat underwent biweekly aPDT, totaling 13 treatment sessions without any adverse events over four months. Gradual weight gain was observed from the first treatment. During the three-year follow-up, there was no recurrence of FCGS. This case report highlights the potential efficacy of topical ICG-aPDT as a treatment modality for FCGS.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on DOAJ: https://doi.org/10.1016/j.pdpdt.2024.104373