Peer-reviewed veterinary case report
Oral tetradecanol gel helps treat gum disease in cats
By Lopes Kubitza, Fernanda Maria & Anthony, James Mudie George·Published in Journal of feline medicine and surgery·2019·Campos de Santo Antonio, Brazil·View original on PubMed →
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Original publication title: Topical oral 1-tetradecanol complex in the treatment of periodontal diseases in cats.
- Species:
- cat
Plain-English summary
A group of cats with chronic gum disease was treated with a special oral gel containing tetradecanol complex (1-TDC) for six weeks. The cats receiving this treatment showed significant improvements in their gum health, including less gum bleeding and reduced pocket depth around their teeth, compared to those given a placebo. While the treatment did not affect tooth mobility, it helped reduce inflammation and other signs of periodontal disease. Overall, the cats treated with 1-TDC had better oral health outcomes after the treatment period.
People also search for: cat gum disease treatment · periodontal disease in cats · tetradecanol for cats · cat dental health improvement
Abstract
OBJECTIVES: The aim of this study was to evaluate the outcomes of the treatment of chronic periodontal disease with an oral application of tetradecanol complex (1-TDC) in cats. METHODS: The test group (n = 9) received 1-TDC (525 mg per gel capsule/day) and the placebo group (n = 4) received olive oil (0.25 ml per gel capsule/day) for 6 weeks. RESULTS: Oral treatment with 1-TDC resulted in significant reductions in all parameters of clinical periodontal disease except tooth mobility at 6 weeks. The 1-TDC group exhibited a statistically significant reduction in pocket depth, clinical attachment loss, gingival index and bleeding on probing after treatment at 6 weeks, whereas the placebo group did not show any significant change. CONCLUSIONS AND RELEVANCE: Chronic inflammation associated with periodontal diseases leads to periodontal tissue destruction. As a result, modulation of the host response has been included in the treatment protocol for periodontal diseases. Fatty acids present anti-inflammatory properties and are being investigated for use in the treatment and prevention of progressive periodontal diseases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30652935/