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Peer-reviewed veterinary case report

Toward a Single-Dose Cure for Buruli Ulcer.

Journal:
Antimicrobial agents and chemotherapy
Year:
2020
Authors:
Thomas, Sangeeta S et al.
Affiliation:
NTU Institute for Health Technologies (HealthTech NTU)

Abstract

A single dose of Q203 (Telacebec), a phase 2 clinical candidate for tuberculosis, eradicatesin a mouse model of Buruli ulcer infection without relapse up to 19 weeks posttreatment. Clinical use of Q203 may dramatically simplify the clinical management of Buruli ulcer, a neglected mycobacterial disease.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/32631818/