Peer-reviewed veterinary case report
Cat survives severe vinblastine overdose with aggressive care
By Grant, I A et al.·Published in The Journal of small animal practice·2010·The Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Toxicities and salvage therapy following overdose of vinblastine in a cat.
- Species:
- cat
Plain-English summary
A cat undergoing chemotherapy for lymphoma accidentally received four times the normal dose of vinblastine, leading to severe and life-threatening side effects. The cat showed signs of electrolyte imbalances, which suggested a condition called SIADH (syndrome of inappropriate secretion of antidiuretic hormone). Fortunately, with prompt and aggressive supportive care from the veterinary team, the cat recovered well. This incident highlights the importance of double-checking medication dosages before treatment.
People also search for: cat lymphoma treatment · vinblastine overdose symptoms · cat chemotherapy side effects
Abstract
A cat receiving chemotherapy for lymphoma was administered a four times overdose of vinblastine in error. Severe, acute life-threatening toxicities occurred. The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) was suspected based on electrolyte disturbances. A favourable outcome was achieved with aggressive supportive care. Personnel involved in administering chemotherapy to small animal patients must check that the patient is receiving the correct drug, at the appropriate dose, prior to every treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20137000/