Peer-reviewed veterinary case report
Three dogs poisoned by swallowing topical moxidectin and imidacloprid
By See, A M et al.·Published in Australian veterinary journal·2009·Murdoch University Veterinary Hospital, Australia·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Toxicity in three dogs from accidental oral administration of a topical endectocide containing moxidectin and imidacloprid.
- Species:
- dog
Plain-English summary
Three dogs were brought to the vet after accidentally swallowing a topical flea and tick treatment that contained moxidectin and imidacloprid. They showed symptoms like muscle tremors, unsteady movements, drooling, confusion, and in two cases, temporary blindness. The vet treated them with methods to remove the toxins from their stomachs, gave them fluids, and used medication to calm their muscle spasms. Thankfully, all three dogs fully recovered within two days.
People also search for: dog drooling and shaking · dog accidental poisoning treatment · moxidectin toxicity in dogs
Abstract
Three dogs were presented with a history of oral administration of a topical endectocide containing imidacloprid and moxidectin. They were diagnosed with imidacloprid and moxidectin intoxication, having ingested doses ranging from 7.5 to 1.4 mg/kg of imidacloprid and 1.9 to 2.8 mg/kg of moxidectin. The three dogs were affected to different degrees of severity, but all displayed signs of ataxia, generalised muscle tremors, paresis, hypersalivation and disorientation. Temporary blindness occurred in two cases. The three dogs were tested for the presence of the multi-drug resistance 1 gene deletion, which can cause an increased sensitivity to the toxic effects of moxidectin, and were found to be negative. Treatment included gastrointestinal decontamination, intravenous fluid therapy and benzodiazepines to control muscle tremors. All three dogs made a complete recovery within 48 h of ingestion.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19673850/