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Peer-reviewed veterinary case report

Dog's kidney protein loss cleared after treating high red blood cells

By Page, R L et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Companion Animal and Special Species Medicine·View original on PubMed

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Original publication title: Transient glomerulonephropathy associated with primary erythrocytosis in a dog.

Species:
dog

Plain-English summary

A dog with primary erythrocytosis (an increased number of red blood cells) was found to have protein in its urine, which can indicate kidney issues. The veterinarian treated the dog with medications and a procedure to remove excess blood, which successfully controlled the erythrocytosis and resolved the proteinuria. The dog remained healthy for about two years after treatment. This case highlights how managing the underlying condition can improve kidney function in dogs.

People also search for: dog protein in urine treatment · dog erythrocytosis symptoms · dog kidney health management

Abstract

Proteinuria (urine protein/creatinine ratio, 13.6) resolved after control of primary erythrocytosis in a dog. Hydroxyurea and doxorubicin administration and phlebotomy were used initially to manage erythrocytosis. Remission was maintained for approximately 2 years. Glomerulonephropathy, characterized by absence of routine histologic or immunofluorescent changes and ultrastructural evidence of basement membrane deterioration and podocyte fusion, was documented. These lesions may have been a result of hypoxia and/or hyperviscosity secondary to erythrocytosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2303386/