Peer-reviewed veterinary case report
Dog with prediabetes got temporary high blood sugar from prednisone
By Murray, S C et al.·Published in Australian veterinary journal·2009·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Transient hyperglycaemia in a prediabetic dog treated with prednisone and cyclosporin A.
- Species:
- dog
Plain-English summary
A dog with immune-mediated hemolytic anemia developed high blood sugar and sugar in the urine after starting treatment with prednisone and cyclosporin A. The vet treated the dog with insulin for a short time, and after that, the dog was able to stay on prednisone without needing more insulin for 12 weeks. Unfortunately, the dog eventually became permanently diabetic. This case suggests that the medications may have made it harder for the dog's body to use insulin properly, but stopping cyclosporin A might have helped reduce that resistance.
People also search for: dog high blood sugar treatment · prednisone side effects in dogs · insulin resistance in dogs
Abstract
A dog with immune-mediated haemolytic anaemia developed transient hyperglycaemia and glucosuria requiring insulin therapy in association with prednisone and cyclosporin A therapy. Following short-term therapy with insulin and cyclosporin A, the dog remained on prednisone therapy but required no further insulin therapy for 12 weeks, at which time the dog became permanently diabetic. We hypothesise that prednisone and cyclosporin A contributed to insulin resistance in a prediabetic dog with suboptimal endogenous insulin concentration and that the degree of insulin resistance decreased when cyclosporin A therapy was discontinued.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19703135/