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Peer-reviewed veterinary case report

Treatment and survival in cats with anal sac gland cancer

By Elliott, James W & Blackwood, Laura·Published in Journal of feline medicine and surgery·2011·University of Liverpool, United Kingdom·View original on PubMed

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Original publication title: Treatment and outcome of four cats with apocrine gland carcinoma of the anal sac and review of the literature.

Species:
cat

Plain-English summary

A 10-year-old male domestic shorthair cat was diagnosed with anal sac adenocarcinoma, a rare type of cancer. The cat underwent surgery to remove the tumor, followed by chemotherapy and radiation therapy. Unfortunately, two cats that received a combination of treatments developed new tumors elsewhere in their bodies, and one had a recurrence of the original tumor. However, one cat that had complete tumor removal is still healthy and cancer-free over a year later. This case highlights the need for better treatments for this aggressive cancer.

People also search for: cat anal sac cancer treatment · anal sac adenocarcinoma in cats · cat cancer survival rates

Abstract

Anal sac adenocarcinoma is uncommon in cats. We report the outcome of multi-modality therapy in two cats (surgery, definitive radiotherapy and systemic chemotherapy) and surgery alone in two cats. All received surgical excision of the primary tumour followed by radiotherapy and carboplatin chemotherapy in two cases. Both cats that underwent multimodal therapy developed distant metastatic disease and one developed recurrence of the primary tumour. One cat that underwent surgery alone with incomplete margins also developed rapid recurrence. Overall survival times were 89, 161 and 169 days. One cat that had complete surgical excision is still alive without recurrence 425 days postoperatively. Whilst the role of radiation in the local control of this disease is yet to be defined, clearly a more effective systemic therapy is required before such aggressive local treatment can be routinely recommended.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21784684/