Peer-reviewed veterinary case report
Stem cell treatment for chronic immune low platelets in a dog
By P.R. Santi et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·2023·View original on DOAJ →
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Original publication title: Treatment of chronic immunomediated thrombocytopenia with mesenquimal stem cells in dog - case report
- Species:
- dog
Plain-English summary
A 5-year-old Pinscher was diagnosed with chronic immunomediated thrombocytopenia, a condition where the immune system destroys platelets, leading to symptoms like bruising and bleeding. Traditional treatments with corticosteroids and immunosuppressants were not enough to manage the condition long-term. The vet then tried a new approach using mesenchymal stem cells from the dog's own fat tissue. This treatment helped maintain healthy platelet levels for over a year, improving the dog's quality of life and eliminating the need for ongoing medication.
People also search for: dog bruising treatment · Pinscher thrombocytopenia · stem cell therapy for dogs
Abstract
ABSTRACT Immunomediated thrombocytopenia is a systemic metabolic disorder in which the platelet count falls below reference values, as the patient's immune system destroys them. The main clinical signs in thrombocytopenia are petechial, hemorrhages, ecchymoses and suffusions. Hematomas can also occur in coagulation disorders. The diagnosis is based on clinical findings and hematological examinations. The treatment consists of the use of corticosteroids and immunosuppressants, delaying cell destruction, and may last for months, not always obtaining a cure for the disease. The present work reports the use of therapy with allogeneic mesenchymal stem cells, derived from the adipose tissue of dogs, for the treatment of chronic immunomediated thrombocytopenia, with an evolution of more than one year, in a Pinscher dog. The alternative treatment showed a good evolution, keeping platelets within the reference values during the treatment, giving the patient quality of life and removing the need for continuous medication for homeostasis after treatment.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1590/1678-4162-12445