Peer-reviewed veterinary case report
Cat mammary tumor treatment with surgery chemo and meloxicam outcomes
By Borrego, J F et al.Ā·Published in Veterinary and comparative oncologyĀ·2009Ā·CMA Hospital, SpainĀ·View original on PubMed ā
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Original publication title: Treatment of feline mammary tumours using chemotherapy, surgery and a COX-2 inhibitor drug (meloxicam): a retrospective study of 23 cases (2002-2007)*.
- Species:
- cat
Plain-English summary
A group of 23 cats with confirmed mammary tumors underwent surgery and received chemotherapy along with a COX-2 inhibitor drug called meloxicam. After surgery, meloxicam was given daily to help manage pain and inflammation. While some cats experienced mild kidney issues, the overall survival time averaged about 460 days, which is similar to other treatment methods. This combination of treatments did not show significant improvement over existing options, suggesting that more research is needed to determine the best approach for treating mammary tumors in cats.
People also search for: cat mammary tumor treatment Ā· meloxicam for cats Ā· feline chemotherapy side effects
Abstract
The efficacy of a treatment combination of a COX-2 inhibitor (meloxicam), chemotherapy and surgery in 23 cats with histologically confirmed mammary gland adenocarcinoma was evaluated. All of the cases underwent an aggressive surgery with concurrent doxorubicin-based chemotherapy. Meloxicam was given orally starting the day after surgery and was continued indefinitely. Serum renal parameters were measured every 3-5 months. Three cats developed azotemia, whereas in four other renal parameters increased but remained within normal limit. The Kaplan-Meier median survival time was 460 days. The Kaplan-Meier median disease free interval was 269 days. The survival times are similar to other studies, not supporting the use of this treatment combination. Prospective studies with a higher number of cases are warranted to investigate the utility of this multimodality protocol for the treatment of feline mammary tumours.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19891691/