Peer-reviewed veterinary case report
Treatment of superficial ulcerative squamous cell carcinoma in three horses with topical 5-fluorouracil.
- Journal:
- The Veterinary record
- Year:
- 1997
- Authors:
- Paterson, S
- Affiliation:
- Animal Medical Centre
- Species:
- horse
Plain-English summary
Three horses were diagnosed with a type of skin cancer called superficial ulcerative squamous cell carcinoma. They were treated with a cream containing a medication called 5-fluorouracil. After just one treatment, two of the horses are still cancer-free, while the third horse is managing the condition with the cream applied for seven days every six weeks. Although there were no serious side effects from the treatment, each horse did experience some localized skin irritation. Overall, the treatment was effective for all three horses.
Abstract
Three horses with superficial ulcerative squamous cell carcinoma were successfully treated with topical 5-fluorouracil. Two of them remain in remission after a single course of treatment and the third case is controlled by the application of the cream for seven days every six weeks. No systemic side-effects were observed but there was a localised inflammatory reaction in the skin in each case.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9447676/