Peer-reviewed veterinary case report
Treatment options and outcomes for T cell lymphoma in dogs
By Moore, Antony S·Published in The Veterinary record·2016·Veterinary Oncology Consultants, United Kingdom·View original on PubMed →
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Original publication title: Treatment of T cell lymphoma in dogs.
- Species:
- dog
Plain-English summary
A dog with T cell lymphoma, a type of cancer affecting the immune system, can have varying outcomes depending on the specific type of lymphoma. Some dogs with a less aggressive form of T cell lymphoma may not need immediate treatment and can have a better prognosis, while those with high-grade T cell lymphoma often face a more challenging battle. Treatment with a common chemotherapy protocol called CHOP can lead to remission in about 40% of cases, but these dogs may relapse sooner and have shorter survival times compared to dogs with other types of lymphoma. It's important for pet owners to discuss the specific type of lymphoma and treatment options with their veterinarian for the best possible outcome.
People also search for: dog T cell lymphoma treatment · canine lymphoma prognosis · chemotherapy for dog cancer
Abstract
Overall, canine lymphoma remains one of the most chemotherapy-responsive cancers in the dog. In addition to the stage and the substage of disease, T cell phenotype is the most consistently important prognostic factor. T cell lymphoma (TCL) in dogs is a heterogeneous disease; dogs with a separate entity of indolent TCL can have a considerably better prognosis than dogs with other forms of lymphoma, and indolent TCL may not always require immediate treatment. In contrast, high-grade TCL is an aggressive disease, and when treated with CHOP-based protocols, dogs with this high-grade TCL have a complete remission rate as low as 40 per cent, relapse earlier and have shorter survival time than dogs with a comparable stage, high-grade B cell lymphoma. This review describes the different disease entities that comprise canine TCL, discusses prognosis for each and treatment options that appear to give the best outcomes.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27634860/