Peer-reviewed veterinary case report
Triphasic nephroblastoma in a horse.
- Journal:
- Journal of comparative pathology
- Year:
- 1996
- Authors:
- Jardine, J E & Nesbit, J W
- Affiliation:
- Department of Pathology
- Species:
- horse
Plain-English summary
A 3-year-old female horse had a large mass in her abdomen that was found during a veterinary exam. Unfortunately, she was humanely euthanized, and the mass was removed for further study. The examination revealed that the mass was a rare type of tumor called triphasic nephroblastoma, which is made up of three different types of tissue. The diagnosis was confirmed by the presence of specific structures in the tumor that helped differentiate it from another type of tumor called a teratoma. The findings provided important insights into how this type of tumor develops.
Abstract
A large abdominal mass in a 3-year-old filly was discovered clinically and removed and examined after the horse had been humanely killed. Histologically, three different tissue types were noted, occurring in equal amounts: epithelium largely in the form of well-differentiated tubules, multifocally distributed cell-dense foci of blastema, and myxoid to fibrous stroma. A diagnosis of triphasic nephroblastoma, a rare tumour in the horse, was made on the basis of microscopical findings. The finding of numerous glomeruloid structures confirmed the diagnosis and assisted in distinguishing the tumour from a teratoma. The histogenesis of nephroblastoma is briefly discussed in the context of the histological and immunohistochemical findings of the case.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8920219/