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Peer-reviewed veterinary case report

Two cases of feline malignant craniopharyngioma.

Journal:
Veterinary pathology
Year:
2005
Authors:
Nagata, T et al.
Affiliation:
Department of Veterinary Pathology · Japan
Species:
cat

Abstract

Tumors at the cranial base in 2 cats (a 9 1/2-year-old, castrated male Chinchilla and a 7-year-old, castrated male American Shorthair) were diagnosed as malignant craniopharyngioma. The tumor lesion was histopathologically divided into four parts: 1) a small acinus part, in which relatively large cells with a pale cytoplasm composed small acini; 2) a duct part, in which small cuboidal cells composed ducts; 3) a cyst part, in which there were large cysts lined with flat cells; and 4) a pavement part, in which large multi-angular-shaped cells proliferated in a pavement pattern. The epithelial cells of some parts were positive for keratin by immunohistochemistry. Histopathologic findings of the present feline cases were identical to those of malignant craniopharyngioma in other animal species.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16145213/