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Peer-reviewed veterinary case report

Unraveling the pathogenesis and prevention strategies of acute high-altitude illness through gut microecology.

Year:
2025
Authors:
Qi P et al.
Affiliation:
The First Clinical Medical College · China

Abstract

High-altitude environments, characterized by hypobaric and hypoxic conditions, induce acute hypoxia, resulting in decreased blood oxygen saturation. This hypoxic stress perturbs gut microecological homeostasis, significantly contributing to the pathogenesis of acute mountain sickness. Consequently, elucidating the mechanisms by which high altitude affects gut homeostasis is crucial for developing effective interventions.

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Original publication: https://europepmc.org/article/MED/40263277