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Peer-reviewed veterinary case report

Dog with diarrhea and fever diagnosed with sterile lymph node

By Dandrieux, Julien R S et al.·Published in Journal of the American Animal Hospital Association·2011·Department of Clinical Veterinary Medicine·View original on PubMed

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Original publication title: Unusual systemic signs in a dog with sterile neutrophilic-macrophagic lymphadenitis and nodular panniculitis.

Species:
dog
LymphomaStomach & digestionDogs

Plain-English summary

A 7-month-old female English Springer Spaniel was brought to the vet because she had diarrhea, vomiting, was very tired, and had a fever. After some tests, the vet found swollen lymph nodes and some lumps under her skin. The dog was diagnosed with a rare condition that caused inflammation in her lymph nodes and skin, but no infections were found. She started treatment with a steroid called prednisolone, but when the dose was lowered, her symptoms returned. The vet then added another medication, cyclosporine, which helped keep her stable, and she has not had any more relapses for over 98 weeks.

People also search for: dog vomiting diarrhea fever · English Springer Spaniel swollen lymph nodes · treatment for dog skin lumps

Abstract

A 7 mo old female English springer spaniel was presented with diarrhea, vomiting, apathy, and hyperthermia. Further examinations revealed generalized lymphadenomegaly consistent with sterile neutrophilic-macrophagic lymphadenitis and pulmonary involvement. Subcutaneous nodules developed one day after presentation. Histology was consistent with sterile idiopathic nodular panniculitis and vasculitis. No infectious organism was isolated. The dog responded to prednisolone, but relapsed during medication tapering. Cyclosporine had to be added to control the disease. No further relapse had occurred 98 wk after the first presentation. This is an unusual presentation of a systemic sterile neutrophilic-macrophagic lymphadenitis with nodular panniculitis and vasculitis associated with gastrointestinal and pulmonary signs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21311075/