Peer-reviewed veterinary case report
Latest treatments and prevention for canine leishmaniasis
By Apostolopoulos, Neoklis et al.·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2018·View original on PubMed →
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Original publication title: Update on therapy and prevention of canine leishmaniasis.
- Species:
- dog
Plain-English summary
A dog with leishmaniasis, an infection spread by sandflies, may show symptoms like skin lesions or weight loss. Some dogs treated with allopurinol, a common medication, developed resistant strains of the infection, leading to recurring issues. New treatment options are being explored, including combinations of miltefosine and allopurinol, as well as meglumine antimoniate. For prevention, several repellents are available, and there are two vaccines in Europe designed to lower the risk of infection and lessen the severity of the disease.
People also search for: dog leishmaniasis treatment · leishmaniasis vaccine for dogs · dog skin lesions treatment
Abstract
Canine leishmaniasis is an emerging infection with increasing importance because the main vector also exists in Germany and autochthonous infections have been described. In this article we present the latest information available regarding therapy and prevention of this disease. Allopurinol-resistantstrains were isolated from dogs which experienced recurrent disease while being treated with allopurinol, highlighting the need for alternative treatment options. Differing results of long-term studies on the efficacy of miltefosine in combination with allopurinol in comparison to meglumine antimoniate and allopurinol can affect the selection of the treatment protocol. A high number of repellents with distinctive characteristics is available for the prevention of infection in dogs. In Europe, two vaccines are licensed for dogs which aim at reducing the risk of an active infection and the severity clinical disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30541172/