Peer-reviewed veterinary case report
New treatments and research updates on dog bone cancer osteosarcoma
By Bryan, Jeffrey N·Published in The Veterinary clinics of North America. Small animal practice·2024·University of Missouri Columbia, United States·View original on PubMed →
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Original publication title: Updates in Osteosarcoma.
- Species:
- dog
Plain-English summary
Osteosarcoma, a type of bone cancer, is a serious condition often seen in dogs. Traditionally, treatment has involved amputating the affected limb and using chemotherapy to manage pain and prolong life. However, new advancements are emerging that could improve outcomes for dogs with this disease. Techniques like limb-sparing surgery, advanced imaging for better diagnosis, and innovative treatments such as immunotherapy and targeted therapies are now available. These options may offer hope for better management and survival rates for dogs diagnosed with osteosarcoma.
People also search for: dog osteosarcoma treatment options · bone cancer in dogs · immunotherapy for dog cancer · limb-sparing surgery for dogs
Abstract
Clinical care of osteosarcoma (OSA) in dogs has seen little change during the past 2 decades, relying on amputation and platinum-based chemotherapy for pain control and survival. Recent advancements offer hope for improved outcomes. Genomic research reveals shared genetic abnormalities between canine and human OSA. Multidimensional imaging provides valuable staging and prognostic information. Limb-sparing approaches including stereotactic body radiation therapy are routine. Ablative therapies such as microwave ablation and histotripsy show promise. Immunotherapy including cell therapy and immune checkpoint inhibition are available. Radiopharmaceuticals are tuned to target OSA cells directly. These innovations may enhance treatment and prognosis for dogs with OSA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38158305/