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Peer-reviewed veterinary case report

Cat with bladder cancer treated by surgery and chemotherapy drugs

By McNally, Abigail et al.·Published in Journal of veterinary internal medicine·2023·Department of Clinical Science and Services, United Kingdom·View original on PubMed

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Original publication title: Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide.

Species:
cat

Plain-English summary

A 4-year-old male neutered domestic shorthair cat was brought to the vet with blood in his urine and difficulty urinating for three months. An ultrasound revealed a large mass in his bladder, which was removed through surgery. After the surgery, the cat received a combination of medications, including cyclophosphamide and thalidomide, for about eight months. Follow-up imaging showed no signs of the cancer returning, and the cat was still doing well nearly two and a half years later.

People also search for: cat blood in urine treatment · cat bladder cancer surgery · hemangiosarcoma in cats prognosis

Abstract

Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4-year-old male neutered domestic shorthair cat was presented with a 3-month history of hematuria and stranguria; ultrasonography identified a large bladder mass. Complete excision was achieved by partial cystectomy. Histopathology and immunohistochemistry for von Willebrand factor confirmed HSA. The cat was treated using adjuvant cyclophosphamide, thalidomide, and meloxicam for 8 months. Abdominal ultrasonography repeated at 2 months and computed tomography repeated at 5 and 19 months after diagnosis showed no evidence of local recurrence or metastasis. The cat was alive at last follow-up (896 days). Although the cat described in this report experienced a more favorable prognosis compared to other visceral HSA locations, additional cases are needed to further understand the biological behavior of bladder HSAs and guide treatment decisions.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37381579/