Peer-reviewed veterinary case report
Urinary and blood creatinine changes in dogs with Babesia canis
By Zygner, Wojciech et al.·Published in Acta parasitologica·2013·Department of Preclinical Sciences·View original on PubMed →
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Original publication title: Urinary creatinine to serum creatinine ratio and renal failure index in dogs infected with Babesia canis.
- Species:
- dog
Plain-English summary
A group of dogs infected with Babesia canis, a parasite that can cause serious illness, showed signs of kidney damage. These dogs had lower levels of a specific kidney function marker compared to healthy dogs, indicating potential renal issues. The study found that the longer the dogs were sick before receiving treatment, the worse their kidney function appeared to be. This suggests that Babesia canis infections can lead to acute kidney problems, highlighting the importance of early diagnosis and treatment.
People also search for: dog kidney problems Babesia canis · signs of kidney failure in dogs · treatment for dog Babesia infection
Abstract
Urinary creatinine to serum creatinine (UCr/SCr) ratio and renal failure index (RFI) are useful indices of renal damage. Both UCr/SCr ratio and RFI are used in differentiation between prerenal azotaemia and acute tubular necrosis. In this work the authors calculated the UCr/SCr ratio and RFI in dogs infected with Babesia canis and the values of these indices in azotaemic dogs infected with the parasite. The results of this study showed significantly lower UCr/SCr ratio in dogs infected with B. canis than in healthy dogs. Moreover, in azotaemic dogs infected with B. canis the UCr/SCr ratio was significantly lower and the RFI was significantly higher than in non-azotaemic dogs infected with B. canis. The calculated correlation between RFI and duration of the disease before diagnosis and treatment was high, positive and statistically significant (r = 0.89, p < 0.001). The results of this study showed that during the course of canine babesiosis caused by B. canis in Poland acute tubular necrosis may develop.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23990425/