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Peer-reviewed veterinary case report

Cat with severe skin lymphoma treated successfully with lomustine

By Komori, Shinobu et al.·Published in Journal of the American Veterinary Medical Association·2005·Nippon Veterinary and Animal Science University, Japan·View original on PubMed

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Original publication title: Use of lomustine to treat cutaneous nonepitheliotropic lymphoma in a cat.

Species:
cat
LymphomaSkin & coatCats

Plain-English summary

A 17-year-old spayed female domestic shorthair cat was brought in for severe skin problems, including painful sores, lumps, redness, and hair loss. After testing, the vet diagnosed her with cutaneous nonepitheliotropic lymphoma, a type of skin cancer. She started treatment with lomustine, a chemotherapy drug, and by the time she received her third dose, her skin lesions had completely cleared up without any serious side effects. This case suggests that lomustine could be an effective treatment option for this type of lymphoma in cats.

People also search for: cat skin cancer treatment · lomustine for cats · cat skin lesions causes

Abstract

A 17-year-old spayed female domestic shorthair cat was referred for evaluation of severe skin lesions, including ulceration, nodule formation, erythema, and alopecia. Cutaneous nonepitheliotropic lymphoma was diagnosed histologically. There was no evidence of visceral organ involvement, but renal function was decreased. The cat was treated with lomustine (45.5 mg/m2, PO, q 21 d), and skin lesions resolved after administration of the third dose. No severe toxicoses were identified. Results suggest that lomustine may be useful for treatment of cutaneous nonepitheliotropic lymphoma in cats; however, optimal dosage, efficacy, and potential adverse effects must be determined.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15706974/