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Peer-reviewed veterinary case report

Propofol for managing seizures in cats and dogs after surgery

By Heldmann, E et al.·Published in The Journal of small animal practice·1999·Department of Clinical Studies, United States·View original on PubMed

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Original publication title: Use of propofol to manage seizure activity after surgical treatment of portosystemic shunts.

Plain-English summary

A dog and four cats had seizures after surgery to correct a liver condition called portosystemic shunts, which can cause serious health issues. In these cases, the veterinarians used propofol, a medication typically used for anesthesia, to help control the seizures. While propofol worked for all the animals, only two of them had a good recovery afterward. This suggests that while propofol can be helpful, it may not always lead to a positive outcome for pets experiencing seizures after such surgeries.

People also search for: dog seizures after surgery · propofol for cat seizures · portosystemic shunt treatment · managing seizures in pets · recovery from seizures in dogs

Abstract

The anaesthetic agent propofol has anticonvulsant properties and has been used in the treatment of refractory status epilepticus in human medicine. This report describes the use of propofol in four cats and one dog with naturally occurring seizures following surgical attenuation of single extrahepatic portosystemic shunts. Two of the animals had seizures that were unresponsive to other anticonvulsants. Subanaesthetic doses of intravenous propofol (1.0 to 3.5 mg/kg boluses and 0.01 to 0.25 mg/kg/minute continuous rate infusions) were used to control the seizures in all animals. However, a good neurological outcome was achieved in only two of the five cases, which is similar to the situation in previous reports.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10664958/