Peer-reviewed veterinary case report
Diagnosing tricky cat viral disease with eye and nerve signs
By de Almeida JCN et al.·2023·Veterinarian, Brazil·View original on Europe PMC →
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Original publication title: Use of selected samples to diagnose a tricky feline viral disease in a cat with uveitis and neurological signs.
- Species:
- cat
Plain-English summary
A 2-year-old mixed-breed cat was brought in with weakness, weight loss, and eye problems, including inflammation (uveitis). After testing, the cat was found to have multiple viral infections, including feline coronavirus (FCoV), feline leukemia virus (FeLV), and feline immunodeficiency virus (FIV). Unfortunately, the cat's condition was severe, and despite efforts to diagnose and treat, it was euthanized due to a poor prognosis. The tests showed that the cat had serious complications, including lymphoma and inflammation of the brain and spinal cord.
People also search for: cat weakness and weight loss · cat eye problems uveitis · feline leukemia virus treatment · feline coronavirus symptoms · cat neurological signs
Abstract
This case involved a 2-year-old neutered male domestic mixed-breed cat that was rescued from the street eight months earlier. The animal presented with weakness, hyporexia, progressive weight loss, fatigue, uveitis, pale mucous membranes, dehydration (7%), and pelvic limb paresis. Aqueous humor was collected for molecular analysis for the differential diagnosis of potential etiological agents [Feline coronavirus (FCoV), Feline leukemia virus (FeLV), Feline immunodeficiency virus (FIV), <i>Toxoplasma gondii</i>, <i>Cryptococcus</i> spp., <i>Felid herpesvirus</i>-1 (FHV-1) and <i>Bartonella</i> spp.] of feline uveitis. The sample was positive by real-time reverse transcription-polymerase chain reaction (RT-qPCR) for FCoV and RT-qPCR and real-time polymerase chain reaction (qPCR) for FeLV and qPCR FIV. The cat was euthanized due to poor clinical outcomes and prognosis. A cerebrospinal fluid (CSF) sample was collected and tested, and the same pathogens were found in the aqueous humor. Small-cell follicular multicenter lymphoma and multifocal pyogranulomatous meningoencephalitis were observed upon histopathological analysis. In this study, aqueous humor and cerebrospinal fluid samples were efficient for the detection of coinfection with FIV, FeLV, and FCoV.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/37521360