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Peer-reviewed veterinary case report

Using C-reactive protein to track inflammation in a dog with immune

By Kristensen Annemarie T et al.·Published in Acta Veterinaria Scandinavica·2006·View original on DOAJ

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Original publication title: Use of serum C-reactive protein as an early marker of inflammatory activity in canine type II immune-mediated polyarthritis: case report

Species:
dog

Plain-English summary

A dog with immune-mediated polyarthritis (IMPA), which was triggered by a tick-borne infection, was monitored for inflammation while receiving steroid treatment. The vet measured the dog's serum C-reactive protein (CRP) levels over 27 weeks to assess inflammation, as traditional white blood cell counts were not helpful during steroid therapy. The results suggested that CRP is a more reliable indicator of inflammation in dogs undergoing this treatment. This approach could help vets better manage similar cases in the future.

People also search for: dog immune-mediated polyarthritis treatment · CRP levels in dogs · dog steroid therapy inflammation

Abstract

<p>Abstract</p> <p>Background</p> <p>Monitoring systemic inflammatory activity during steroid therapy of canine immune-mediated polyarthritis (IMPA) is difficult and mainly relies on clinical signs.</p> <p>Case presentation</p> <p>Canine serum C-reactive protein (CRP) was measured serially and blinded during a 27-week follow-up period of a case of <it>Anaplasma phagocytophilia </it>induced type II immune-mediated polyarthritis.</p> <p>Conclusion</p> <p>WBC was, as expected, observed not to reflect the inflammatory activity during steroid treatment in a clinical useful manner, whereas, CRP is suggested a valuable unbiased marker of inflammatory activity during steroid treatment in this case.</p>

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Original publication on DOAJ: https://doi.org/10.1186/1751-0147-48-9