Peer-reviewed veterinary case report
Alendronate drug eased bone cancer pain in two dogs
By Tomlin, J L et al.·Published in The Veterinary record·2000·The Royal Veterinary College·View original on PubMed →
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Original publication title: Use of the bisphosphonate drug alendronate for palliative management of osteosarcoma in two dogs.
- Species:
- dog
Plain-English summary
A 10-year-old dog with a bone tumor in the leg and a 7-year-old dog with a tumor in the jaw were treated with a medication called alendronate to help manage their pain and improve their comfort. The dog with the leg tumor had a spiral fracture that healed after a special device was used to stabilize it. Both dogs were able to live comfortably for several months after their diagnosis, with one living for 12 months and the other for 10 months, even though their tumors were not surgically removed.
People also search for: dog osteosarcoma treatment · alendronate for dogs · dog bone cancer pain management
Abstract
The bisphosphonate drug alendronate was used to suppress bone remodelling and tumour osteolysis as a palliative treatment for two dogs with osteosarcoma, one of the tibia and one of the maxilla. A spiral fracture associated with the tibial tumour healed after it was stabilised with an external skeletal fixator. Both dogs remained comfortable and survived for 12 and 10 months respectively after diagnosis, despite the fact that neither primary tumour was resected.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10958534/