Usefulness of laparoscopy guided renal biopsy in dogs.

Abstract

Renal biopsies were carried out in 25 mixed-breed dogs of both sexes, aged 6 to 11 years, using an automatic, laparoscopy-guided method. The aim of the study was to apply and evaluate the usefulness of this technique in the diagnosis of renal pathologies in dogs. Twenty biopsy specimens were obtained from the right kidney and five--from the left kidney. As many as 24 of the 25 effectively collected biopsy specimens were classified as excellent (96%). Significant histopathological changes were found in 23 of the 25 biopsies performed. The results of histopathological analyses show a predominance of glomerular lesions over interstitial lesions, mostly mesangial glomerulonephritis, membranous and membrane-proliferative glomerulonephritis. The study confirmed that laparoscopy-guided biopsy of the kidney in dogs is a safe and a highly useful diagnostic technique. The results of histopathological analyses of biopsy specimens correlated with clinical history, clinical examination results, blood and urine tests and ultrasound examination results have a great diagnostic value and they significantly affect treatment and prognosis. Laparoscopy-guided biopsy supports the diagnosis and differentiation of glomerular and interstitial lesions and renal neoplasia in dogs.