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Peer-reviewed veterinary case report

Using Naturally Occurring Bioluminescent Enzymes to Track Specific Cell Populations.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2020
Authors:
Shrestha, Tej B & Basel, Matthew T
Affiliation:
Department of Anatomy and Physiology · United States

Abstract

Luminol-based bioluminescence imaging allows noninvasive tracking of oxidatively active cells such as neutrophils. Luminol is given intravenously or intraperitoneally, followed by bioluminescence imaging at 425 nm. Here we describe a method for tracking neutrophil extravasation into an inflammatory site, especially focusing on mammary carcinoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/32112375/