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Peer-reviewed veterinary case report

Cat with uterine cancer and widespread tumor spread

By Cooper, T K et al.·Published in Veterinary pathology·2006·Department of Comparative Medicine, United States·View original on PubMed

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Original publication title: Uterine myxoid leiomyosarcoma with widespread metastases in a cat.

Species:
cat

Plain-English summary

A 10-year-old domestic shorthair cat was brought in for surgery to remove ovarian masses and an enlarged uterus. During the procedure, the vet found large cystic masses and multiple nodules in the uterus, which were later diagnosed as a type of cancer called myxoid leiomyosarcoma. Unfortunately, the cancer had spread throughout the cat's abdomen and chest, and despite treatment, the cat was euthanized a month later due to suspected tumor recurrence. This case highlights the aggressive nature of this type of cancer in cats.

People also search for: cat cancer symptoms · domestic shorthair tumor treatment · cat ovarian mass surgery · what is myxoid leiomyosarcoma in cats

Abstract

A 10-year-old domestic shorthair cat was spayed to remove bilateral ovarian masses and an enlarged uterus. Both ovaries were effaced by large, irregular, firm, glistening, white cystic masses filled with clear viscous fluid. The uterine lumen was filled with copious amounts of clear viscous fluid, and the uterus contained multiple, firm, glistening, white nodules. Histologic examination revealed an invasive spindle cell neoplasm with features of malignancy, and extensive hypocellular areas containing an alcian blue-positive myxoid matrix. Tumor cells expressed caldesmon, alpha-smooth muscle actin, and estrogen receptor but were negative for desmin. The animal was euthanized 1 month later because of suspected local tumor recurrence. At necropsy, the abdominal cavity contained 120 ml of mucoid ascites; multiple tumor nodules were present in the abdominal and thoracic cavities. The clinical behavior and gross, microscopic, and immunohistochemical findings established a diagnosis of myxoid leiomyosarcoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16846999/