Peer-reviewed veterinary case report
Vaginal fold prolapse in a dog with pyometra and ovarian papillary cystadenocarcinoma.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 2016
- Authors:
- Zedda, Maria-Teresa et al.
- Species:
- dog
Plain-English summary
A 7-year-old female Italian Mastiff weighing 42 kg was brought in because she had a vaginal prolapse, which is when part of the vagina slips out of place, during a specific stage of her heat cycle. During the examination, the vet found that her uterus was enlarged and there were some concerning changes in her ovaries, including a cyst. Blood tests showed signs of infection and mild anemia. The dog underwent surgery to remove her uterus and ovaries, and the prolapsed tissue was put back in place. After the surgery, the vaginal issue completely resolved within 35 days, and five months later, she was doing well overall.
Abstract
CASE DESCRIPTION: A 7-year-old 42-kg (92.4-lb) sexually intact nulliparous female Italian Mastiff was examined because of a history of vaginal prolapse during diestrus. CLINICAL FINDINGS: A physical examination revealed vaginal fold prolapse. Abdominal ultrasonography revealed an enlarged uterus with hypoechogenic content, corpora lutea in the ovaries, and a cyst in the right ovary. Hematologic abnormalities included leukocytosis, neutrophilia, mild anemia, and low Hct. Progesterone and estradiol concentrations were 9.36 ng/mL and 30.42 pg/mL, respectively, in serum and 72.72 ng/mL and 792 pg/mL, respectively, in the ovarian cystic fluid. TREATMENT AND OUTCOME: Ovariohysterectomy was performed; the prolapsed tissue was repositioned by external manipulation and maintained in situ by temporary apposition of the vulvar lips with a retention suture. Anatomic and histologic examinations of the excised tissues revealed pyometra and papillary cystadenocarcinoma in the right ovary. The vaginal hyperplasia completely regressed at 35 days after surgery; 5 months after surgery, the dog's general condition was considered good. CLINICAL RELEVANCE: Findings in this case were indicative of a hormonally active ovarian papillary cystadenocarcinoma in a female dog in diestrus. Hormone production by the cystadenocarcinoma was the predisposing factor that induced pyometra, mucosal hyperplasia, and vaginal fold prolapse in the dog. On the basis of these concurrent disorders, ovariohysterectomy was an appropriate treatment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27003024/