Peer-reviewed veterinary case report
Dog with vertebral telangiectatic osteosarcoma causing movement
By Brellou, G et al.·Published in Veterinary clinical pathology·2004·Department of Veterinary Pathology·View original on PubMed →
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Original publication title: Vertebral telangiectatic osteosarcoma in a dog.
- Species:
- dog
Plain-English summary
A 4-year-old male dog was brought in for trouble moving, which was found to be caused by a type of bone cancer called telangiectatic osteosarcoma affecting the seventh cervical vertebra in his neck. X-rays and other imaging showed bone damage and a mass pressing on the spinal cord. The diagnosis was confirmed through a tissue examination, revealing a tumor with large blood-filled spaces and abnormal cells. Treatment options for this type of cancer can vary, and it's important to discuss with your veterinarian for the best approach.
People also search for: dog neck pain · dog bone cancer treatment · why is my dog having trouble moving
Abstract
Telangiectatic osteosarcoma (TOS) affecting the seventh cervical vertebra (C7) was diagnosed in a 4-year-old male dog with signs of locomotor dysfunction. Bone lysis and an extradural-extramedullary mass were observed in radiographs and occipital myelograms. The diagnosis was confirmed by histopathologic and immunohistochemical examination of the mass. The tumor was composed of large blood-filled cavities lined by anaplastic stromal cells (malignant osteoblasts). Around the cavities were characteristic tumor giant cells ("bizarre cells"). Immunohistochemically the tumor cells were positive for proliferating cell nuclear antigen. The lining cells of the cysts were negative for von Willebrand factor. The histologic findings in this case of TOS involving C7 were similar to those seen in other cases of TOS in dogs and in people. Immunohistochemistry was a useful tool for assessing malignancy and for ruling out other differential diagnoses.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15334352/