Peer-reviewed veterinary case report
Cat with vulvar swelling and bleeding caused by leiomyosarcoma
By Firat, Ibrahim et al.·Published in Journal of feline medicine and surgery·2007·Department of Pathology·View original on PubMed →
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Original publication title: Vulvar leiomyosarcoma in a cat.
- Species:
- cat
Plain-English summary
An 8-year-old mixed-breed cat was brought to the vet with symptoms of vulvar swelling, bleeding, and difficulty urinating. After examination, the vet found a mass at the vulva, which was diagnosed as a type of cancer called vulvar leiomyosarcoma. This tumor is made up of abnormal smooth muscle cells and showed signs of necrosis and bleeding. Treatment options for this type of cancer can vary, and it's important for pet owners to discuss the best approach with their veterinarian.
People also search for: cat vulvar swelling bleeding · cat cancer treatment options · what is leiomyosarcoma in cats
Abstract
A vulvar leiomyosarcoma was diagnosed in an 8-year-old mixed-breed, sexually intact cat. The cat had a history of vulvar swelling, bleeding and stranguria. The mass was located at the ventral commissura of the vulva. The cut surface of the mass was lobulated and greyish-white, with areas of necrosis and haemorrhage. Histologically, it was a spindle-cell sarcoma consisting of interlacing bundles of very elongated neoplastic smooth muscle cells and variably dense collagenous matrix separated by individual cells or streams. It also contained areas of focal necrosis and haemorrhage. The mitotic index ranged from seven to 12 mitoses per 10 high-power fields. Immunohistochemically, the spindle-shaped neoplastic cells were strongly positive for smooth muscle actin (SMA) and vimentin, whereas no immunoreactivity was obtained for desmin. The vascular elements of the internal control tissue also exhibited strong SMA and vimentin immunoreactivity. Based on the morphological and immunohistochemical features, the tumour was classified as a leiomyosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17601762/