Peer-reviewed veterinary case report
Western blot blood test for diagnosing food allergy in dogs
By Favrot, Claude et al.·Published in Veterinary dermatology·2017·Clinic for Small Animal Internal Medicine·View original on PubMed →
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Original publication title: Western blot analysis of sera from dogs with suspected food allergy.
- Species:
- dog
Plain-English summary
A group of 38 dogs with skin issues suspected to be caused by food allergies were put on an elimination diet to see if their symptoms improved. The dogs were tested using a new method called Cyno-DIAL to help choose the right diet. While Cyno-DIAL showed some promise, it wasn't reliable enough to confirm food allergies on its own. Ultimately, the elimination diet helped classify 14 dogs as food allergic, while others did not show food-related issues. This suggests that while the Cyno-DIAL test can assist in selecting diets, it shouldn't be solely relied upon for diagnosing food allergies.
People also search for: dog food allergy symptoms · elimination diet for dogs · Cyno-DIAL test for dog allergies
Abstract
BACKGROUND: Food allergy is often suspected in dogs with clinical signs of atopic dermatitis. This diagnosis is confirmed with an elimination diet and a subsequent challenge with regular food. Laboratory tests for the diagnosis of food allergy in dogs are unreliable and/or technically difficult. Cyno-DIALis a Western blot method that might assist with the selection of an appropriate elimination diet. HYPOTHESIS/OBJECTIVES: To evaluate the performance of Cyno-DIALfor the selection of an elimination diet and diagnosis of food allergy. ANIMALS/METHODS: Thirty eight dogs with atopic dermatitis completed an elimination diet. Combining the results of the diet trials and the challenges, 14 dogs were classified as food allergic (FA), 22 as nonfood-allergic and two as ambiguous cases. RESULTS: Amongst all dogs and amongst dogs with a clinical diagnosis of FA, 3% and 7% (respectively) were positive to Royal Canin Anallergenic, Vet-Concept Kanguruor Vet-Concept Dog Sana; 8% and 7% to Hill's d/d Duck and Rice; 8% and 21% to Hill's z/d Ultra Allergen Free; 53% and 64% to Eukanuba Dermatosis FP; and 32% and 43% to a home-cooked diet of horse meat, potatoes and zucchini. The specificity and sensitivity of Cyno-DIALfor diagnosing food allergy were 73% and 71%, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: Although Cyno-DIALwas considered potentially useful for identifying appropriate foods for elimination diet trials, it cannot be recommended for the diagnosis of food allergy. The Cyno-DIALtest performed better than some previously evaluated ELISA-based tests.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28090706/