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Peer-reviewed veterinary case report

Swollen lymph node in dog caused by fungal infection

By Dunbar, Mark D & Wamsley, Heather L·Published in Veterinary clinical pathology·2009·Department of Physiological Sciences, United States·View original on PubMed

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Original publication title: What is your diagnosis? Lymph node cytology from a dog.

Species:
dog
LymphomaBreathing & coughDogs

Plain-English summary

A 2-year-old mixed-breed dog was brought to the vet with swelling, sores, and draining areas around his left ankle. Tests showed he had an infection in his lymph nodes caused by a type of fungus called Lagenidium caninum. The vet confirmed this by checking for specific antibodies in the dog's blood. Treatment details weren't provided, but identifying the exact cause of the infection is crucial for effective treatment.

People also search for: dog swollen lymph nodes · dog skin infection treatment · mixed-breed dog with draining sores

Abstract

A 2-year-old, castrated male, mixed-breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine-needle aspirate specimens of the left popliteal lymph node revealed pyogranulomatous lymphadenitis with hyphal organisms. The diameters of the hyphae were variable, ranging from 11 to 22 microm. The organism was considered as most consistent with Lagenidium caninum; although Pythium insidiosum or Lagenidium karlingii were not conclusively excluded, hyphal diameter in these organisms is typically smaller (6.6-8.8 and 2.5-11 microm, respectively). A positive Western blot confirmed the presence of serum antibodies reactive against Lagenidium sp. and the absence of antibodies to P. insidoisum, Basidiobolus, and Conidiobolus antibodies. Careful assessment of hyphal diameter in cytologic specimens may be useful in differentiating L. caninum from P. insidiosum or L. karlingii.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19228367/