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Peer-reviewed veterinary case report

Why Do Some Primate Malarias Relapse?

Journal:
Trends in parasitology
Year:
2016
Authors:
White, Nicholas J
Affiliation:
Faculty of Tropical Medicine · United Kingdom

Abstract

Relapse may have evolved in malaria as a mechanism to avoid suppression by more virulent species in mixed infections, thereby increasing transmission opportunities. Later evolution of long latency in Plasmodium vivax was a necessary adaptation as early hominins moved to colder areas with shorter mosquito breeding seasons. Genetic diversity was maintained through heterologous hypnozoite activation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27743866/