Peer-reviewed veterinary case report
Ovarian tumor spread to heart muscle in 5-year-old German boxer dog
By Sabocanec, R et al.·Published in Acta veterinaria Hungarica·1996·Department of Pathology·View original on PubMed →
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Original publication title: A case of metastasizing ovarian granulosa cell tumour in the myocardium of a bitch.
- Species:
- dog
Plain-English summary
A 5-year-old German Boxer was diagnosed with a malignant ovarian tumor that had spread to her heart and lungs. The dog showed no specific symptoms mentioned, but the tumor was found during routine examinations, including X-rays that revealed a significant mass in her abdomen. Unfortunately, the cancer had already metastasized to multiple areas, including her heart and lymph nodes. Treatment options for such advanced cases can be limited, and the prognosis is often poor.
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Abstract
Clinical examinations including X-ray analysis, gross pathological, histopathological and ultrastructural investigations were performed on a case of ovarian granulosa cell tumour in a 5-year-old German boxer bitch. Radiographic examination of the abdomen revealed a round, sharply demarcated formation about 4-5 cm in size. The tumour of the left ovary was of a malignant granulosa cell type, with numerous metastases 5-20 mm in size, present in the myocardium (left ventricle), lungs (in all lobes) and prescapular lymph node. Ultrastructural characterization of the tumour demonstrated closely packed cells, with rough endoplasmic reticulum, indicating markedly enhanced protein synthesis probably associated with rapid cell proliferation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8908742/