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Peer-reviewed veterinary case report

A quadrigeminal dermoid cyst with concurrent necrotizing granulomatous leukoencephalomyelitis in a Yorkshire Terrier dog.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2011
Authors:
Beard, Philippa M et al.
Affiliation:
The Roslin Institute and Royal (Dick) School of Veterinary Studies · United Kingdom
Species:
dog

Abstract

A 2-year-old female Yorkshire Terrier dog presented with neurological deficits. Magnetic resonance imaging revealed an 8 mm in diameter mass centered left of midline arising from the quadrigeminal cistern, with a fatty or proteinaceous content. A further fat signal intensity focus was present in the tip of the temporal horn of the right lateral ventricle, in keeping with a "floating" fat embolus within the cerebrospinal fluid. A ruptured dermoid cyst was diagnosed. Within the frontal lobe on both sides were ill-defined and extensive high T2 signal areas, with mass effect within the white matter, and asymmetrical contrast enhancement following intravenous injection of gadolinium. Postmortem gross and histological examination confirmed the mass in the quadrigeminal cistern to be a dermoid cyst. In addition, severe multifocal necrotizing granulomatous leukoencephalomyelitis was found in the corona radiata and spinal cord. The relationship between these 2 pathologies is discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21908379/