Peer-reviewed veterinary case report
Jaw reconstruction after tumor removal in dogs with acanthomatous
By Tsugawa, Anson J et al.·Published in Frontiers in veterinary science·2022·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: A Retrospective Study on Mandibular Reconstruction Following Excision of Canine Acanthomatous Ameloblastoma.
- Species:
- dog
Plain-English summary
Eleven dogs with a type of jaw tumor called acanthomatous ameloblastoma underwent surgery to remove the tumor, which left a significant gap in their jaw. To repair this gap, veterinarians used a special titanium plate and a material that helps bone grow, infused with a growth factor. After surgery, all dogs showed signs of healing, with new bone forming within a month, and they returned to their normal activities, eating and drinking without issues. While there were a few minor complications, none of the dogs experienced tumor regrowth or major problems with the repair.
People also search for: dog jaw tumor treatment · acanthomatous ameloblastoma surgery · dog jaw reconstruction recovery
Abstract
The successful excision of a locally invasive tumor such as canine acanthomatous ameloblastoma (CAA) typically results in a mandibular contour-derforming, critical-size defect that alters the jaw kinematics, and may affect the patient's quality of life. In this case series, we describe our experience using the regenerative approach of a titanium locking plate and compression resistant matrix infused with rhBMP-2 for the immediate or delayed reconstruction following mandibulectomy for the excision of mandibular CAA in 11 dogs. Surgical planning included computed tomography (CT), with and without contrast, in all cases, and 3D-printed models in four cases. Tumor-free surgical margins were achieved in all dogs. Clinical and diagnostic imaging follow-up (mean, 23.1 months) were performed in-person (11 cases) and with CT/cone-beam computed tomography in most cases, with standard radiography (3 cases) and telemedicine being utilized in 5 cases. At 2 weeks postoperatively, hard tissue was palpable at the defect. Follow-up imaging at 1 month postoperatively revealed evidence of bridging new bone with a heterogeneous appearance, that remodeled over 3-6 months to bone of a similar size, shape and trabecular pattern as native bone. Histological evaluation of regenerated bone was available in two cases, and was supportive of our clinical and imaging findings of normal remodeled bone. Clinically, all dogs returned to a normal lifestyle, rapidly resumed eating and drinking, and exhibited normal occlusion. Complications included wound dehiscence in one dog and self-limiting exuberant bone formation in two dogs. Tumor regrowth, failure of the implant or fracture of the regenerated bone were not observed. We conclude that the mandibular reconstruction using a regenerative approach is safe, feasible, and results in restoration of mandibular contour in dogs following segmental and bilateral rostral mandibulectomy for benign but invasive oral tumors such as CAA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35647098/