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Peer-reviewed veterinary case report

Cat with severe anemia and abnormal red blood cell growth

By Iwanaga, Tomoko et al.·Published in The Journal of veterinary medical science·2012·Department of Veterinary Medicine, Japan·View original on PubMed

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Original publication title: Abnormal erythroid cell proliferation and myelofibrosis in a cat.

Species:
cat

Plain-English summary

A cat was brought in with severe anemia, meaning it had a low red blood cell count, and was getting worse despite having many immature red blood cells in its bone marrow. Tests showed it did not have common viral infections that affect cats. The veterinarian tried immunosuppressive therapy, but it didn’t help, so they diagnosed the cat with a condition affecting blood cell production. The cat showed some improvement with a medication called cytarabine but sadly passed away about seven weeks later due to complications from the disease.

People also search for: cat anemia treatment · myelodysplastic syndrome in cats · cat bone marrow disease symptoms

Abstract

A cat was presented with severe progressive anemia despite marked erythroblastosis. The cat was negative for feline leukemia virus antigen and feline immunodeficiency virus antibody. Bone marrow cytology revealed an excess of erythroid cells with a predominance of prorubricytes and basophilic rubricytes. No response to immunosuppressive therapy was obtained, and a tentative diagnosis of myelodysplastic syndrome was made. The cat showed a partial response to low-dose cytarabine (20 mg/m(2) subcutaneously q24) but died 51 days after the 1st admission. Histopathological examination revealed fibrosis in the bone marrow and marked infiltration of erythroid cells into other organs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22313965/