Peer-reviewed veterinary case report
Swelling in Shih Tzu's lower jaw caused by amyloid tumor
By Tsai, Y-C et al.·Published in Veterinary pathology·2007·Graduate Institute of Veterinary Medicine, China·View original on PubMed →
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Original publication title: Amyloid-producing odontogenic tumor and its immunohistochemical characterization in a Shih Tzu dog.
- Species:
- dog
Plain-English summary
A 10-year-old male Shih Tzu was brought to the vet with swelling in his lower jaw, which was caused by a mass in his gums. X-rays showed that the bone in his jaw was being damaged by the growth. After examining the tissue, the vet diagnosed it as an amyloid-producing odontogenic tumor, which is a type of tumor that can form in the mouth. The treatment plan would typically involve surgical removal of the tumor, but the specific outcome isn't mentioned.
People also search for: Shih Tzu jaw swelling · dog mouth tumor treatment · amyloid tumor in dogs
Abstract
A 10-year-old, male, Shih-Tzu dog presented with swelling of the right lower jaw caused by a mass arising from the right mandibular gingiva. Radiographic examination revealed bone lysis of the right wing of the mandible. Histopathologically, the growth was characterized by indistinctly lobulated nests, islands, and strands of proliferating odontogenic and squamous epithelial cells, intermingled in close association with large numbers of irregular extracellular deposits of amyloid and amorphous calcified substance. Immunohistochemically, both epithelial components stained strongly positive for cytokeratin (AE1/AE3); the squamous epithelial cells also reacted strongly with neuron-specific enolase (NSE) and S-100 protein, whereas the odontogenic epithelial cells displayed weak immunoreactivity to NSE and partial reactivity to S-100 protein. The amyloid deposits were AE1/AE3-negative. The growth was diagnosed as an amyloid-producing odontogenic tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17317805/