Peer-reviewed veterinary case report
Antibiotic resistance in Staphylococcus from dogs with skin
By Kawakami, Tetsuji et al.·Published in The Journal of veterinary medical science·2010·The United Graduate School of Veterinary Sciences, Japan·View original on PubMed →
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Original publication title: Antimicrobial susceptibility and methicillin resistance in Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans isolated from dogs with pyoderma in Japan.
- Species:
- dog
Plain-English summary
A study found that many dogs in Japan with skin infections (pyoderma) had bacteria called Staphylococcus pseudintermedius and Staphylococcus schleiferi that were resistant to common antibiotics. Out of 190 samples, a significant number of the Staphylococcus pseudintermedius bacteria were resistant to methicillin, a common antibiotic used to treat infections. This means that treating skin infections in these dogs can be challenging, as many antibiotics may not work effectively. The findings highlight the importance of testing for antibiotic resistance to choose the right treatment for affected dogs.
People also search for: dog skin infection treatment · antibiotic resistance in dogs · pyoderma in dogs symptoms
Abstract
To understand species distribution, trends of antimicrobial susceptibility and prevalence of methicillin resistance in canine staphylococci in Japan, 190 coagulase-positive staphylococci (CoPS) were isolated from dogs with pyoderma in 2 Japanese veterinary referral hospitals. Using a multiplex polymerase chain reaction (M-PCR) method, two CoPS species were identified: 170 Staphylococcus pseudintermedius (89.5%) and 20 S. schleiferi subsp. coagulans isolates (10.5%). In these isolates, susceptibility to 7 antimicrobial agents was determined. Overall, the levels of susceptibility to cefalexin (CEX), amoxicillin/clavulanic acid (CVA/AMPC), minocycline (MINO), ofloxacin (OFLX), norfloxacin (NFLX), lincomycin (LCM) and clindamycin (CLDM) in S. pseudintermedius isolates were 38.2, 52.4, 34.7, 31.2, 34.1, 1.2 and 11.2%, respectively. In S. schleiferi subsp. coagulans isolates, 55% demonstrated susceptibility to CEX, 80% to CVA/AMPC, 70% to MINO, 45% to OFLX or NFLX and 30% to CLDM. None of S. schleiferi subsp. coagulans isolates was susceptible to LCM. To determine the prevalence of methicillin-resistant strains, we used a PCR method, which enabled detection of the fragment of mecA gene in 66.5% (113 of 170) in S. pseudintermedius and 30.0% (6 of 20) in S. schleiferi subsp. coagulans isolates. The frequencies of susceptibility to CEX, CVA/AMPC, OFLX, NFLX and CLDM were significantly lower in methicillin-resistant CoPS than in methicillin-susceptible CoPS isolates. These data suggest a high level of methicillin resistance in staphylococci isolated from dogs with pyoderma in Japan.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20703027/