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Peer-reviewed veterinary case report

Aplastic anemia in two kittens following a prescription error.

Journal:
Journal of the American Animal Hospital Association
Year:
2008
Authors:
Paul, April L et al.
Affiliation:
Department of Clinical Sciences · United States
Species:
cat

Abstract

A medication error resulted in two kittens being treated with azathioprine (12 and 12.5 mg/kg) instead of azithromycin for 2 weeks. On clinical examination, the kittens were febrile, weak, and had oronasal hemorrhage. Complete blood cell counts indicated severe bone marrow suppression. Treatment consisted of multiple transfusions, antibiotics, and granulocyte colony-stimulating factor. One of the kittens responded to therapy and had a complete recovery. The other kitten was treated for 40 days with no clinical response before dying. Both kittens also contracted Mycoplasma hemofelis infection from a contaminated blood transfusion.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18175796/