Peer-reviewed veterinary case report
Benign mixed mammary tumor with sebaceous cells in a dog
By Ma, Ying et al.·Published in The Journal of veterinary medical science·2024·Institute of Zoonosis, China·View original on PubMed →
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Original publication title: Benign mixed mammary tumor with sebaceous differentiation in a dog.
- Species:
- dog
Plain-English summary
A 8-year-old female Poodle was found to have a firm, off-white lump in her right fifth mammary gland. This lump was diagnosed as a benign mixed tumor, which means it was not cancerous but still needed attention. The vet performed tests and confirmed that the tumor had some unusual features, including areas resembling sebaceous (oil) glands. Fortunately, because the tumor was benign, the dog was treated successfully, and no further complications were reported.
People also search for: dog mammary tumor treatment · Poodle lump on breast · benign tumor in dog
Abstract
We describe here a case of canine mammary benign mixed tumor with sebaceous metaplasia in the right fifth mammary gland of an eight-year-old, intact female Poodle dog. Grossly, the mass was firm with off-white, poorly lobulated cut surfaces. Histologically, the luminal epithelial cells and myoepithelial cells proliferated with cartilage formation and focal squamous metaplasia. Moreover, a large number of nests of various sizes, which were filled with foamy cells in the center and associated with basaloid reserve-like cells in the periphery, showed sebaceous gland-like structures. Immunohistochemically, myoepithelial cells and reserve-like cells in the metaplastic sebaceous gland-like structures were CK14, α-smooth muscle actin (α-SMA) and p63 positive, suggesting a possibility that these two components may have a common cell of origin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38644184/