Peer-reviewed veterinary case report
Bone marrow failure and feminization in male German Shepherd
By Suess, R P et al.·Published in Journal of the American Veterinary Medical Association·1992·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Bone marrow hypoplasia in a feminized dog with an interstitial cell tumor.
- Species:
- dog
Plain-English summary
A 10-year-old male German Shepherd was brought in with symptoms like fever, pale gums, abdominal pain, and an unusually large left testicle, while the right testicle was smaller than normal. Tests revealed low blood cell counts and signs of infection, and a bone marrow sample showed signs of aplastic anemia (a condition where the bone marrow doesn't produce enough blood cells). The dog also had high levels of estrogen and low testosterone, indicating feminization, and a tumor was found in the left testicle. Unfortunately, the treatment details and outcome were not provided, but this case highlights the importance of checking for underlying issues when unusual symptoms arise.
People also search for: dog testicular tumor · German Shepherd anemia symptoms · why is my dog feverish and weak
Abstract
Bone marrow hypoplasia and feminization developed in a 10-year-old male German Shepherd Dog with interstitial cell tumor. Clinical abnormalities included pyrexia, pale mucous membranes, signs of abdominal pain, large left testis, atrophied right testis, and feminization. Abnormal laboratory findings included pancytopenia, bacteremia, bacteriuria, and pyuria. Results of cytologic examination of a bone marrow aspirate were consistent with aplastic anemia. Serum estradiol concentration was high, and serum testosterone concentration was low, compared with normal values for male dogs. The left testicular mass was identified as an interstitial cell tumor. Other causes of the aplastic anemia or feminization were not found.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1601719/