Peer-reviewed veterinary case report
Canine Acute Eosinophilic Dermatitis with Edema (Wells-Like Syndrome).
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2019
- Authors:
- Mauldin, Elizabeth A
- Affiliation:
- Department of Pathobiology · United States
- Species:
- dog
Plain-English summary
Canine acute eosinophilic dermatitis with edema, also known as Wells-Like Syndrome, is a rare skin condition in dogs. Dogs with this syndrome often have a history of stomach issues, like vomiting or diarrhea, before or at the same time as they develop skin problems. The main signs include redness and swelling, especially on the smooth skin of the belly. While the exact cause isn't clear, it might be related to a bad reaction to a medication or an allergic response. This condition can sometimes be confused with another skin issue called canine sterile neutrophilic dermatosis because they share similar symptoms.
Abstract
Canine acute eosinophilic dermatitis with edema is an uncommon syndromic disorder in dogs with a unique clinical presentation. Most but not all dogs have a history of gastrointestinal upset preceding or concomitant with skin lesion onset. Affected dogs present with macular to generalized erythema that is most evident on the glabrous skin of the abdomen. Although the etiology is not known, an adverse drug reaction or a systemic type I hypersensitivity reaction may play a role. Some cases can be difficult to distinguish from canine sterile neutrophilic dermatosis due to overlapping clinical criteria and eosinophil degranulation in tissue section.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30390793/